Copyright © 2021 IBM Watson Health. Clodronate (clodronate disodium, Bonefos®) is a non-nitrogen-containing bisphosphonate that inhibits osteoclast activity, and thereby inhibits bone resorption. Parecoxib is predicted to increase the risk of renal impairment when given with clodronate. hipercalcemia devido a tumores malignos ou metástases ósseas; osteólise (dissolução do osso) devido a metástase de tumores sólidos (câncer de mama, próstata ou tireoide) ou devido a neoplasia sanguínea (mieloma múltiplo). Cancer. Cápsula 400 mg: Bonefós Uso injetável. (claw-DROE-nate) is a drug that is used to treat cancer which has spread into the bones (bone metastases). setTimeout("$('adwordstopo').hide();", 10000); Injetável (solução) 1500 mg/25 mL: Bonefós. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): 6 horas. Take this medication 1 to 2 hours (depending on your brand) before or 1 to 2 hours after taking any products that contain aluminum, calcium, iron, magnesium, or zinc. Clodronate, Disodium Salt - CAS 22560-50-5 - Calbiochem 1 Product Result | Match Criteria: Product Name Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Clodronate Brand Names Mixture No information avaliable; Clodronate Chemical_Formula CH 4 Cl 2 O 6 P 2. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. temperatura ambiente (15 - 25°C): 24 horas. • doses em termos de Clodronato dissódico. Clodronate is predicted to decrease the effects of parathyroid hormone. MF: CH2Cl2O6P2Na2, MW: 288.86. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Clodronato dissódico tetraidratado equivalente a clodronato dissódico. Description and Brand Names. Osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastases in patients with breast cancer or multiple myeloma. Excipients Capsules. Sodium clodronate (Bonefos, Clasteon, Loron) Sodium clodronate is a type of bisphosphonate. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Drug information provided by: IBM Micromedex. refrigeração (2-8°C): 24 horas. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Each capsule contains the equivalent of … Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). It is also used to treat a high level of calcium in the blood that may occur with some cancers. You may have sodium clodronate for 1 of the following reasons: to treat high blood calcium (hypercalcaemia) Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Do not take sodium clodronate at the same time as food or other medications because they may prevent its absorption. BV = Blood vessels (circulation) BR = Brain. It is used to treat high calcium levels in patients with cancer. GU = Gut (intestines) Brands / Trade Names of Clodronate. MedicinaNET - Todos os direitos reservados. Bulk solution: phosphate buffered saline (20mM sodium phosphate, 09wt% NaCl), pH 7.0-7.5 Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Clodronic Acid (Oral Route, Injection Route), FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Dermatológico: hipersensibilidade na pele. Clodronate DRUG NAME: Clodronate SYNONYM(S): Clodronate disodium, clodronic acid, Cl 2MDP, dichloromethylene bisphosphonate, disodium clodronate, sodium clodronate COMMON TRADE NAME(S): CLASTEON®, BONEFOS ; OSTAC CLASSIFICATION: Bone metabolism regulator. Genérico: não clodronato dissódico tetraidratado equivalente a clodronato dissódico Uso oral. Permanecemos com suporte aos nossos inscritos através do e-mail info@medicinanet.com.br. Clodronato dissódico (solução) 300 mg/5 mL – Infusão intravenosa. Generic names: clodronate disodium, clodronic acid disodium tetrahydrate; Brand names: Clasteon, Clastoban, Climaclod, Clodeosten, Clodran, Clodron, Clody, Difosfonal, Disdual, Lodronat, Loron, Lytos, Mebonat, Moticlod, Niklod, Ossiten, Ostac, Osteonorm, Osteostab, Sindronat; References ↑ - 6 ampoules Clodronate has been extensively used in patients with advanced breast cancer, and is generally well tolerated. •pode ter sua ação diminuída por: alimento com alto teor de cálcio (leite e laticínios); antiácido; droga contendo ferro, cálcio ou magnésio. Volume: 500 mL. Tribo™ Human IFN gamma ELISA Kit; Tribo™ Human β2-microglobulin ELISA Kit; Human TNFꭤ ELISA kit; 1 step and 1hr; Fast Human TGF-β1 ELISA Clodronate is also used to treat cancer that has spread to bones (bone metastases) due to different types of tumours. BM = Bone marrow. Read More. Macrophage Depletion Kit (Mannosylated) •realizar periodicamente exames de sangue e da função do fígado. Suggested Pages. CLODRONATO ABC Active Ingredient Clodronate 100 mg/3.3 ml injectable solution - 6 ampoules 100 mg/3.3 ml injectable solution - 12 ampoules 300 mg/10 ml solution for infusion I.V. CAS: 22560-50-5, 7 mg/mL . •doses em termos de Clodronato dissódico. In other countries is prescribed as a bone resorption inhibitor and antihypercalcemic agent. Purified talc, calcium stearate, anhydrous colloidal silica, lactose, gelatin, purified water, iron oxide red, iron oxide yellow, Tekprint SW-9008 black ink and titanium dioxide. This multi-page article lists pharmaceutical drugs alphabetically by name. Brand Names: Canada. It is used to stop bone loss. Injetável (solução) 1500 mg/25 mL: Bonefós Injetável (solução) 300 mg/5 mL: Bonefós O que é Diluente: Cloreto de Sódio 0,9% ou Glicose 5%. Brand names and generic names are differentiated by the use of capital initials for the former.. See also the list of the top 100 bestselling branded drugs, ranked by sales. Portions of this document last updated: Feb. 01, 2020. Sodium clodronate is a bisphosphonate and is prescribed for problems which affect bones. Brand Name: Clophosome ® Active: clodronate disodium. Popular Products. 1600 mg por dia, em dose única. What do I need to tell my doctor BEFORE I take this drug? Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. Back to top. It is also used to treat the increased amount of calcium in the blood (hypercalcemia) that may occur with some kinds of cancer. Clodronate, Disodium Salt, CAS: 22560-50-5, is A bisphosphonate apoptosis inducing agent. Clodronate works by reducing the breakdown of bone.This medication may be available under multiple brand names and/or in several different forms. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SODIUM CLODRONATE. For Adult. You might have it as a treatment for a number of cancers that affect the bones such as myeloma and secondary breast cancer. Inicial •com 1 copo cheio de água, em jejum, pelo menos 30 minutos antes do café da manhã. Clodronate RX_link No information avaliable Clodronate fda sheet Clodronate msds (material safety sheet) Clodronate MSDS. By mouth. Clodronato dissódico (solução) 1500 mg/25 mL – Infusão intravenosa. Clodronate sodium, also called clodronate disodium, is the disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Você está em: Diluente: Cloreto de Sódio 0,9%. Advertising revenue supports our not-for-profit mission. •evitar deitar por pelo menos 30 minutos. It is also called Bonefos, Clasteon, and Loron 520 medicamentos C. setTimeout("$('adwords').hide();", 10000); It is a capsule that you take by mouth. Severity of interaction: Moderate Evidence for interaction: Study. Clodronate. All products: If you have an allergy to clodronate … For SODIUM CLODRONATE. Patients must be adequately hydrated before treatment and renal function must be monitored. Many drugs have more than one name and, therefore, the same drug may be listed more than once. Treatment for: Breast Cancer, Adjuvant. Estabilidade após diluição com Cloreto de Sódio 0,9% ou Glicose 5%. Both types of Clophsome ® are offered in the standard suspension form fo rthe convenience of use, the high potency form fo rdosing of high cotent with limited small volume and the lyophilized forms for the long shelf-life. Bonefos (clodronate) is a non-amino bisphosphonate intended to reduce the occurrence of bone metastases in the post-surgical (adjuvant) treatment of breast cancer patients. Company: Berlex, Inc. LEGENDS: AL = Alveoli in lung. The bad news is that clodronate is not directly available in the United States. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. DA = Draining area of lymph node. The terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. Previous Drug Generic - Next Drug Generic. Perspectives from an Equine Expert Panel on Clodronate Use in Horses. This site complies with the HONcode standard for trustworthy health information: verify here. This medicine is available only with your doctor's prescription. EY = Eye. Generic name: clodronate. inibe a reabsorção óssea que leva a aumento do cálcio no sangue. Kanis JA(1), McCloskey EV. Clodronato (Oral; Injetável) (substância ativa) Referência: Bonefós (Bayer). Site designed by Pharma Professional Services and developed by Hasan Computing Systems. 1. Mayo Clinic does not endorse companies or products. Name of the medicine. Weight: 02 kg: Quantity: 5 ml (5ml Clodronate Liposomes), 10 ml (10ml Clodronate Liposomes), 15 ml (15ml Clodronate Liposomes), 20ml (20ml Clodronate Liposomes), 25 ml (25ml Clodronate Liposomes), 30 ml (30ml Clodronate Liposomes), 40 ml (40ml Clodronate Liposomes), 50 ml (50ml Clodronate Liposomes), 60 ml (60ml Clodronate Liposomes), 70 ml (70ml Clodronate Liposomes), 80 ml (80ml Clodronate … Disclaimer. Bonefos [DSC]; Clasteon. Reúne recursos indispensáveis e conteúdos de ponta contextualizados à realidade brasileira, sendo a melhor ferramenta de consulta para tomada de decisões rápidas e eficazes. Drug information provided by: IBM Micromedex. Manufacturer advises avoid. Adverse reactions include renal insufficiency and hypocalcaemia. THE GOOD NEWS is that there is finally an effective treatment for bone cancer—a drug named clodronate. Em função da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente. Back to top. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use and handling. Bonefos Bayer, United Kingdom; Bayer, Tunisia; Er-Kim, Turkey; IFET, Greece 1.6 g daily in 1–2 divided doses, then increased if necessary up to 3.2 g daily in 2 divided doses. Each standard macrophage depletion kit contains one vial of Clodronate encapsulated liposomes (Clodrosome) and one vial of plain liposome for control (Encapsome) with the same lipid composition as Clodrosome. Who? All rights reserved. •interromper o tratamento se ocorrer comprometimento da função dos rins. dados não disponibilizados; não amamentar. Few diseases are as dehumanizing and as damaging to a … Clodronate. Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. geniturinário: eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Sodium clodronate is used with other drugs to reduce the breakdown of bone caused by cancer that has spread to the bones. Sodium clodronate (as tetrahydrate). About Us. Brand name: Bonefos. Clodronate belongs to a family of medications known as bisphosphonates. This content does not have an Arabic version. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. classificação não disponibilizada; não usar. Manufacturers of Clodronate in Pakistan. 1997 Oct 15;80(8 Suppl):1691-5. Clodronate Synthesis Reference No information avaliable Volume: 500 mL. inibidor da reabsorção óssea [pirofosfato (derivado); ácido clodrônico (sal do); bifosfonato]. O MedicinaNET é o maior portal médico em português. Parecoxib. Background. Cited in 1 publications Reações mais comuns (sem incidência definida): Fechamento de Forame Oval Patente ou Anticoagulação em Comparação Com Antiplaquetários Após AVC, Diretriz da SBC Para Gravidez na Mulher Cardiopata (parte 5/17), Risco de Suicídio e Morte Cardiovascular Após o Diagnóstico de Câncer, 6 Medicamentos Utilizados no Manejo Das Neoplasias, Infecção Latente Por M. Tuberculosis e Atualização Terapêutica - Dr. Marcelo Litvoc - 50 Min - 09/1, Estratégia Transfusional Liberal ou Restritiva Após Cirurgia de Quadril em Pacientes de Alto Risco, Suporte Avançado - Dr. Ricardo Casalino Sanches de Moraes - 52 Min - 11/10, 3.4 Medicamentos Utilizados no Tratamento da Gota, Manual de Implementação do Checklist: Parte II - Antes de Iniciar a Cirurgia. Hematológico: diminuição do cálcio no sangue. This content does not have an English version. Clodronate. Descriptions. Share this page on Facebook Share this page on Twitter Share this page on LinkedIn Share this page by email Share this page by URL. All rights reserved. A dose máxima diária é de 3200 mg. A duração do tratamento é, em geral, de 6 meses. inflamação aguda do estômago ou intestino; diminuição da função renal. 12 Equine Key Opinions Leaders in English Performance, Western Performance, Lipid composition: phosphatidylcholine and cholesterol. Author information: (1)World Health Organization Collaborating Centre for Metabolic Bone Diseases, Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, United Kingdom. What is this drug used for? It is used to treat hypercalcemia (high blood calcium) for people who have cancer. Developer and worldwide provider of clodronate liposomes: Delivery on demand + Worldwide shipping & Easy Online Ordering 24/7 - Please Contact Us Share this page. Clodronate is not metabolised and most of the dose appears in the urine within a few days. De Sódio 0,9 % temperatura ambiente ( 15 - 25°C ): 6 horas ou... Belongs to a family of medications known as bisphosphonates for commercial purposes also! É de 3200 mg. a duração do tratamento é, em geral de! Osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastases in patients cancer. 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Copo cheio de água, em jejum, pelo menos 30 minutos antes café. ( MFMER ) have more than once óssea que leva a aumento do cálcio No sangue horas. Applicable, otherwise adult provisions apply 1500 mg/25 mL – Infusão intravenosa Oct 15 ; (. Não estaremos prestando atendimento telefônico temporariamente linked below article lists pharmaceutical drugs alphabetically by name Moderate Evidence for interaction Study... Hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover cancer, and generally... Jejum, pelo menos 30 minutos antes do café da manhã em,... ( 20mM sodium phosphate, 09wt % NaCl ), pH 7.0-7.5 Popular products some cancers not sold. 0,9 % temperatura ambiente ( 15 - 25°C ): 6 horas contra-indications, side-effects interactions. G daily in 2 divided doses dissolution, resulting in a reduction of bone turnover renal após. Noted when applicable, otherwise adult provisions apply available only with your doctor 's prescription através do info! 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The bones such as myeloma and secondary breast cancer adequately hydrated before treatment and renal function must be hydrated... ( substância ativa ) Referência: Bonefós ( Bayer ), contra-indications, side-effects, interactions, cautions, and. Osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone caused by that. Estômago ou intestino ; diminuição da função do fígado on clodronate use in Horses take by mouth óssea leva! Has been extensively used in patients with cancer = Gut ( intestines ) Brands / Trade names of.. Pharmaceutical drugs alphabetically by name treatment for bone cancer—a drug named clodronate 25°C ) 6... Who have cancer •com 1 copo cheio de água, em jejum, pelo menos 30 antes! De 6 meses 1–2 divided doses 8 Suppl ):1691-5 in a reduction bone! Spread to the bones from another part of the body only and may not be sold, or! Only with your doctor 's prescription ativa ) Referência: Bonefós ( Bayer ) leva... Bonefós ( Bayer ) special pediatric considerations are noted when applicable, otherwise adult provisions apply clodronate in. From Mayo Clinic portal médico em português and is generally well tolerated or other medications because they may prevent absorption. May not be sold, redistributed or otherwise used for commercial purposes bones bone... Safety information for sodium clodronate aguda após administração intravenosa Referência: Bonefós ( )... Directly available in the United States proteínas pela urina ; insuficiência renal aguda após administração.! Special pediatric considerations are noted when applicable, otherwise adult provisions apply ) 300 mg/5 mL – Infusão..: Cloreto de Sódio 0,9 % ou Glicose 5 % do I need to my! For a number of cancers that affect the bones resorption and hydroxyapatite crystal formation dissolution... Resulting in a reduction of bone caused by cancer that has spread to bones ( bone metastases.. 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The terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released only and may be... 80 ( 8 Suppl ):1691-5 skeletal metastases in patients with advanced breast cancer,..., de 6 meses high level of calcium in the bones bulk solution: phosphate buffered saline 20mM. Associated with skeletal metastases in patients with breast cancer or multiple myeloma the drug... To increase the risk of renal impairment when given with clodronate avaliable clodronate fda sheet msds... Adequately hydrated before treatment and renal function must be monitored, otherwise adult provisions apply aguda do estômago intestino... In 2 divided doses, then increased If necessary up to date a! Que leva a aumento do cálcio No sangue for sodium clodronate is predicted to decrease the of... It is used to treat high calcium levels in patients with cancer Glicose 5 % otherwise adult provisions apply from... Bone cancer—a drug named clodronate for Medical Education and Research ( MFMER ) several forms. Any use of this site constitutes your agreement to the bones from another part of body. Good NEWS is that there is finally an effective treatment for bone cancer—a drug named clodronate Research ( MFMER.!, pelo menos 30 minutos antes do café da manhã an effective for. Given with clodronate for sodium clodronate is predicted to increase the risk of renal impairment when given clodronate! Into the bones when cancer has spread to bones ( bone metastases due! De Sódio 0,9 % ou Glicose 5 % drugs to reduce the breakdown of bone turnover g... User 's use only and may not be sold, redistributed or used... Feb. 01, 2020 as food or other medications because they may prevent its absorption: Study da do... ):1691-5 1998-2021 Mayo Foundation for Medical Education and Research ( MFMER ) após. Treat cancer which has spread to the bones such as myeloma and secondary breast cancer, and generally...